加载中…
Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.
io.github.cyanheads/chembl-mcp-server 是 ChatHome Skills 收录的 MCP 条目，来源为 Official MCP Registry，质量分 78/100。 作为 Model Context Protocol 服务器，它向 Claude、Cursor、Copilot 等兼容 MCP 的 LLM 客户端暴露可直接调用的工具，让 agent 的能力超出模型内置范围。 该条目由 ChatHome Skills 的每日抓取从官方 registry 和 GitHub 发现查询中收录，每次运行都会重新核验仓库事实、新鲜度信号和安装元数据。 质量分综合了官方 registry 收录情况、可用安装命令、许可证完整性、仓库活跃度和 GitHub star 趋势，完整算法说明见来源页。安装命令已列于上方，可直接复制使用。 在将 io.github.cyanheads/chembl-mcp-server 加入生产 agent 工作流前，请核对上方的最近更新日期和仓库状态——下方事实快照是最近一次抓取的时点值。
mcp add io.github.cyanheads/chembl-mcp-server https://chembl.caseyjhand.com/mcp运行此命令前，请先核对上游源码。
{
"_meta": {
"io.modelcontextprotocol.registry/official": {
"status": "active",
"isLatest": true,
"updatedAt": "2026-10-24T12:49:49.071479Z",
"publishedAt": "2026-10-24T12:49:49.071479Z",
"statusChangedAt": "2026-10-24T12:49:49.071479Z"
}
},
"server": {
"name": "io.github.cyanheads/chembl-mcp-server",
"$schema": "https://static.modelcontextprotocol.io/schemas/2025-12-11/server.schema.json",
"remotes": [
{
"url": "https://chembl.caseyjhand.com/mcp",
"type": "streamable-http"
}
],
"version": "0.4.1",
"packages": [
{
"version": "0.4.1",
"transport": {
"type": "stdio"
},
"identifier": "@cyanheads/chembl-mcp-server",
"runtimeHint": "npx",
"registryType": "npm",
"registryBaseUrl": "https://registry.npmjs.org",
"environmentVariables": [
{
"name": "CANVAS_PROVIDER_TYPE",
"format": "string",
"default": "duckdb",
"description": "DataCanvas provider for the bioactivity spill and the chembl_dataframe_* SQL tools; DuckDB is the default. Set to 'none' to disable it: large bioactivity sets then inline a preview but never spill."
},
{
"name": "CHEMBL_API_BASE_URL",
"format": "string",
"default": "https://www.ebi.ac.uk/chembl/api/data",
"description": "Base URL for the ChEMBL REST data API. Override for a private mirror or pinned host."
},
{
"name": "CHEMBL_REQUEST_TIMEOUT_MS",
"format": "string",
"default": "30000",
"description": "Per-attempt timeout in milliseconds for an upstream ChEMBL request, capped by what is left of the call's time budget (45 s for most calls, CHEMBL_SPILL_DEADLINE_MS for a bioactivity spill)."
},
{
"name": "CHEMBL_MAX_PAGE_SIZE",
"format": "string",
"default": "1000",
"description": "Rows per upstream ChEMBL page (max 1000). The bioactivity spill walks pages of this size; an inline bioactivity page requests its limit, capped at this size."
},
{
"name": "CHEMBL_DEFAULT_LIMIT",
"format": "string",
"default": "25",
"description": "Default result limit applied when callers omit it."
},
{
"name": "CHEMBL_MAX_SPILL_ROWS",
"format": "string",
"default": "50000",
"description": "Ceiling on rows chembl_get_bioactivities stages to a DataCanvas table, and so on the upstream page walk behind it. Over the cap the response reports truncated: true and truncated_by: \"row_cap\"."
},
{
"name": "CHEMBL_MAX_CONCURRENT_PAGES",
"format": "string",
"default": "4",
"description": "Most chembl_get_bioactivities spill-page requests in flight at once (1–6), shared by every call on the server."
},
{
"name": "CHEMBL_SPILL_DEADLINE_MS",
"format": "string",
"default": "45000",
"description": "Time budget in milliseconds for one chembl_get_bioactivities spill, its count and page walk (10000–600000). At expiry the rows fetched so far stage with truncated: true and truncated_by: \"time_budget\"."
},
{
"name": "CHEMBL_DATAFRAME_DROP_ENABLED",
"format": "string",
"default": "false",
"description": "Set to 'true' to register the opt-in chembl_dataframe_drop tool (absent from tools/list when off)."
},
{
"name": "MCP_LOG_LEVEL",
"format": "string",
"default": "info",
"description": "Sets the minimum log level for output (e.g., 'debug', 'info', 'warn')."
}
]
},
{
"version": "0.4.1",
"transport": {
"url": "http://localhost:3010/mcp",
"type": "streamable-http"
},
"identifier": "@cyanheads/chembl-mcp-server",
"runtimeHint": "npx",
"registryType": "npm",
"registryBaseUrl": "https://registry.npmjs.org",
"environmentVariables": [
{
"name": "MCP_TRANSPORT_TYPE",
"value": "http",
"format": "string",
"description": "Selects the HTTP transport."
},
{
"name": "MCP_HTTP_HOST",
"format": "string",
"default": "127.0.0.1",
"description": "The hostname for the HTTP server."
},
{
"name": "MCP_HTTP_PORT",
"format": "string",
"default": "3010",
"description": "The port to run the HTTP server on."
},
{
"name": "MCP_HTTP_ENDPOINT_PATH",
"format": "string",
"default": "/mcp",
"description": "The endpoint path for the MCP server."
},
{
"name": "MCP_AUTH_MODE",
"format": "string",
"default": "none",
"description": "Authentication mode to use: 'none', 'jwt', or 'oauth'."
},
{
"name": "MCP_LOG_LEVEL",
"format": "string",
"default": "info",
"description": "Sets the minimum log level for output (e.g., 'debug', 'info', 'warn')."
},
{
"name": "CANVAS_PROVIDER_TYPE",
"format": "string",
"default": "duckdb",
"description": "DataCanvas provider for the bioactivity spill and the chembl_dataframe_* SQL tools; DuckDB is the default. Set to 'none' to disable it: large bioactivity sets then inline a preview but never spill."
},
{
"name": "CHEMBL_API_BASE_URL",
"format": "string",
"default": "https://www.ebi.ac.uk/chembl/api/data",
"description": "Base URL for the ChEMBL REST data API. Override for a private mirror or pinned host."
},
{
"name": "CHEMBL_REQUEST_TIMEOUT_MS",
"format": "string",
"default": "30000",
"description": "Per-attempt timeout in milliseconds for an upstream ChEMBL request, capped by what is left of the call's time budget (45 s for most calls, CHEMBL_SPILL_DEADLINE_MS for a bioactivity spill)."
},
{
"name": "CHEMBL_MAX_PAGE_SIZE",
"format": "string",
"default": "1000",
"description": "Rows per upstream ChEMBL page (max 1000). The bioactivity spill walks pages of this size; an inline bioactivity page requests its limit, capped at this size."
},
{
"name": "CHEMBL_DEFAULT_LIMIT",
"format": "string",
"default": "25",
"description": "Default result limit applied when callers omit it."
},
{
"name": "CHEMBL_MAX_SPILL_ROWS",
"format": "string",
"default": "50000",
"description": "Ceiling on rows chembl_get_bioactivities stages to a DataCanvas table, and so on the upstream page walk behind it. Over the cap the response reports truncated: true and truncated_by: \"row_cap\"."
},
{
"name": "CHEMBL_MAX_CONCURRENT_PAGES",
"format": "string",
"default": "4",
"description": "Most chembl_get_bioactivities spill-page requests in flight at once (1–6), shared by every call on the server."
},
{
"name": "CHEMBL_SPILL_DEADLINE_MS",
"format": "string",
"default": "45000",
"description": "Time budget in milliseconds for one chembl_get_bioactivities spill, its count and page walk (10000–600000). At expiry the rows fetched so far stage with truncated: true and truncated_by: \"time_budget\"."
},
{
"name": "CHEMBL_DATAFRAME_DROP_ENABLED",
"format": "string",
"default": "false",
"description": "Set to 'true' to register the opt-in chembl_dataframe_drop tool (absent from tools/list when off)."
}
]
}
],
"repository": {
"url": "https://github.com/cyanheads/chembl-mcp-server",
"source": "github"
},
"description": "Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications."
}
}