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Computes and interprets sequencing read depth and coverage over a genome, windows, or target regions with mosdepth (windowed depth, cumulative distribution, --quantize callable BEDs), bedtools genomecov/coverage (bedGraph tracks, per-target stats), samtools depth/coverage (per-base depth, per-contig depth+breadth). Covers the breadth-vs-mean distinction, the cumulative-coverage curve, evenness (CV/Fano/fold-80/Gini), what each tool silently counts (duplicates, secondary/supplementary, MAPQ, read span vs fragment, mate-overlap), the samtools-depth 8000-cap version trap, and the bedtools coverage -a/-b orientation flip. Use when assessing sequencing adequacy, building coverage tracks, computing breadth at a depth threshold, defining callable regions, or QCing target-capture uniformity.
bio-genome-intervals-coverage-analysis is an agent skill entry in ChatHome Skills, sourced from GitHub Skill Search and scored 58/100. ## Version Compatibility Reference examples tested with: bedtools 2.31+, mosdepth 0.3+, samtools 1.19+, pybedtools 0.10+, numpy 1.26+. Before using code pattern. As an agent skill, it packages a reusable instruction set that AI coding agents such as Codex and Claude Code can load to perform this task without hand-written glue code. ChatHome Skills discovered this entry through its daily ingest of official registries and GitHub discovery queries, and re-verifies repository facts, freshness signals, and install metadata on every run. The quality score weighs official-registry presence, a working install command, license clarity, GitHub star trajectory, and repository freshness — the full formula is on the Sources page. The install command above is ready to copy. Review the last-pushed date and repository status before adding bio-genome-intervals-coverage-analysis to a production agent workflow; the snapshot facts below are point-in-time values from the most recent ingest.
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## Version Compatibility Reference examples tested with: bedtools 2.31+, mosdepth 0.3+, samtools 1.19+, pybedtools 0.10+, numpy 1.26+. Before using code patterns, verify installed